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Gene Expression Literature Summary
Assay
Age
Western blot
16.5 DPC

19 matching records from 19 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dab1  disabled 1   (Synonyms: C630028C02Rik)
Results  Reference
1J:109820 Arnaud L, Ballif BA, Forster E, Cooper JA, Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol. 2003 Jan 8;13(1):9-17
1*J:90089 Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA, Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol. 2004 Apr 6;14(7):606-10
1*J:138800 De Gasperi R, Gama Sosa MA, Wen PH, Li J, Perez GM, Curran T, Elder GA, Cortical development in the presenilin-1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin-dependent signaling. Dev Dyn. 2008 Sep;237(9):2405-14
1*J:265269 Dhananjaya D, Hung KY, Tarn WY, RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development. Mol Cell Biol. 2018 Jun 15;38(12)
1J:145031 Feng L, Cooper JA, Dual functions of Dab1 during brain development. Mol Cell Biol. 2009 Jan;29(2):324-32
1J:174747 Franco SJ, Martinez-Garay I, Gil-Sanz C, Harkins-Perry SR, Muller U, Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Neuron. 2011 Feb 10;69(3):482-97
1*J:186654 Gao Z, Poon HY, Li L, Li X, Palmesino E, Glubrecht DD, Colwill K, Dutta I, Kania A, Pawson T, Godbout R, Splice-mediated motif switching regulates disabled-1 phosphorylation and SH2 domain interactions. Mol Cell Biol. 2012 Jul;32(14):2794-808
1*J:74239 Herrick TM, Cooper JA, A hypomorphic allele of dab1 reveals regional differences in reelin-Dab1 signaling during brain development. Development. 2002 Feb 1;129(3):787-96
1J:91679 Herrick TM, Cooper JA, High affinity binding of Dab1 to Reelin receptors promotes normal positioning of upper layer cortical plate neurons. Brain Res Mol Brain Res. 2004 Jul 26;126(2):121-8
1J:153525 Hurtado-Chong A, Yusta-Boyo MJ, Vergano-Vera E, Bulfone A, de Pablo F, Vicario-Abejon C, IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone. Eur J Neurosci. 2009 Sep;30(5):742-55
1J:299731 Kohno T, Ishii K, Hirota Y, Honda T, Makino M, Kawasaki T, Nakajima K, Hattori M, Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. J Neurosci. 2020 Oct 21;40(43):8248-8261
1J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86
1J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78
1J:250180 Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S, Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015 Jun 10;5:11163
1*J:120590 Ohshima T, Suzuki H, Morimura T, Ogawa M, Mikoshiba K, Modulation of Reelin signaling by Cyclin-dependent kinase 5. Brain Res. 2007 Apr 6;1140:84-95
1J:85055 Petrone A, Battaglia F, Wang C, Dusa A, Su J, Zagzag D, Bianchi R, Casaccia-Bonnefil P, Arancio O, Sap J, Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J. 2003 Aug 15;22(16):4121-31
1J:50400 Rice DS, Sheldon M, D'Arcangelo G, Nakajima K, Goldowitz D, Curran T, Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development. 1998 Sep;125(18):3719-29
1J:171375 Senturk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A, Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature. 2011 Apr 21;472(7343):356-60
1J:116689 Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y, Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration. J Neurosci. 2006 Dec 20;26(51):13357-62

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory